Global Journal of Medical Research, A: Neurology & Nervous System, Volume 23 Issue 3

or remain stable in older adults. Moreover, can be a helpful tool for the researchers to explore why some older individuals maintain strong executive functioning skills while others experience declines, potentially uncovering protective factors or interventions that promote cognitive health. Conclusions To conclude CLOX: An Executive Clock-Drawing is a reliable and valid tool in the Greek population with the disorders described above suggesting that the CLOX assessment shows promise as a valuable tool for assessing executive function in individuals with specific disorders. Despite the positive findings in the Greek population with the described disorders, it is important to validate the reliability and validity of the CLOX assessment in other populations and with a broader range of disorders. This will help establish the generalizability of the findings and determine if the CLOX assessment can be used as a reliable tool across different clinical and research contexts. This ongoing research will enhance our understanding of the value and applicability of the CLOX assessment. Supplementary Materials: Not applicable Author Contributions: Conceptualization Eleni Sideri; George P.Paraskevas; investigation, Eleni Sideri; Ioanna Tsantzali; resources, Georgios N. Papadimitropoulos, Claire Kelly, Dimitrios Kitsos, Stella Fanouraki, Angeliki Sterpi; writing—original draft preparation, Eleni Sideri; Ioanna Tsantzali; formal analysis, Eleni Sideri; George P.Paraskevas; George Tsivgoulis writing—review and editing, George Papadimitropoulos, Eleni Sideri, Claire Kelly; supervision, George P.Paraskevas, and Konstantinos Voumvourakis. All authors have read and agreed to the published version of the manuscript. Funding: Not applicable Institutional Review Board Statement: 'BNEYR, EBD366/16-7-2021, Informed Consent Statement: Informed consent was obtained from all subjects involved in the study, also, there is written informed consent has been obtained from the participants to publish any paper related to this data. Data Availability Statement: Due to restrictions of the ethics committee patients’ data cannot become publicly available, however, they may be provided by the correspondent author according to a reasonable request Acknowledgments: We sincerely thank Professor Donald Royall for his license to translate, validate, and use the CLOX: an executive drawing task and conduct this study Conflicts of Interest: Not applicable. R eferences R éférences R eferencias 1. Achiron, A. (2003). Cognitive impairment in probable multiple sclerosis. Journal of Neurology, Neurosurgery & Psychiatry , 74 (4), 443–446. https://doi.org/10.1136/jnnp.74.4.443 2. Allott, K., Fisher, C. A., Amminger, G. 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