Global Journal of Medical Research, F: Diseases, Volume 22 Issue 1

II. R esearch P urpose Improvement of the results of treatment of patients with purulent-destructive diseases of soft tissues with the help of local complex application of PDT and CO 2 laser. III. M aterials and M ethods The study is based on the results of a comprehensive examination and treatment of 360 patients with purulent wounds of soft tissues who were treated in the department of purulent surgery of the 1- city clinical hospital on the basis of the Department of Surgical Diseases of the TMA from 2014 to 2019. Depending on the treatment carried out, the patients were conditionally divided into 3 groups: the 1st (control group) included 118 patients who underwent conventional traditional methods of treatment; in the 2nd group (main group I) there were 120 patients who, in combination with traditional methods of treatment, used PDT with a photosensitizer (PS) 0.05% buffer solution of methylene blue (MS); and the 3rd group (main group II) included 122 patients where PDT was used in combination with traditional methods of treatment (0.05% methylene blue buffer solution was used as PS) and a CO2 laser. According to our data, the distribution of patients by age and sex is presented in table 1. Among the examined patients, there were 189 (52.5%) women, 171 (47.5%) men, the age of the patients varied from 18 to 82 years. The main contingent of patients was of working age from 18 to 60 years - 277 patients (63%). Table 1: Distribution of patients depending on age and gender Age of the patients Control group Main group I Main group II Men Women Men Women Men Women From 18 to 44 years old 18 23 19 26 21 20 From 45 to 59 years old 15 17 16 18 19 15 From 60 to 74 years old 11 14 15 11 14 17 75 and elder 9 11 5 10 9 7 Total (%) 53(45%) 65(55%) 55(46%) 65(54%) 63(51,6%) 59(48,3) According to clinical entities in patients, erysipelas prevailed in 63 patients (17.5%), carbuncle in 53 patients (14.8%), infected wounds in 48 patients (13.4%), phlegmon in 43 patients (11.9%) and postoperative suppuration of wounds of various localization in 34 patients (9.5%). Table 2: Clinical entities of examined patients No. Nosology Control group Main group I Main group II Total 1. Erysipelas 23 29 11 63(17,5%) 2. Carbuncle 17 11 25 53(14,8%) 3. Infected wound 19 22 7 48(13,4%) 4. Phlegmon 12 13 18 43(11,9%) 5. Postoperative wound suppuration 10 9 15 34(9,5%) 6. Abscessed furuncle 7 8 13 28(7,8%) 7. Soft tissue abscess 8 4 10 22(6,1%) 8. Postinjective abscess 7 8 6 21(5,8%) 9. Acute suppurative mastitis 5 6 9 20(5,5%) 10. Suppurative hematoma 7 5 4 16(4,4%) 11. Other nosology 3 5 4 12(3,3%) Total 118 120 122 360(100%) Analyzing table 3 on the location of a purulent wound, it can be noted that most often purulent wounds were localized in the body area 98 (27.3%) and lower limbs -73 (20.3%). 2 Year 2022 Global Journal of Medical Research Volume XXII Issue I Version I ( D ) F © 2022 Global Journals Optimization of Treatment Methods for Purulent-Destructive Soft Tissue Diseases through the use of Laser Treatment Methods