Global Journal of Medical Research, F: Diseases, Volume 22 Issue 1

Table 14: Comparative characteristics of planimetric indicators of purulent wounds in dynamics in the studied groups Group of patients Wound area (cm 2 and %) 1 st day 3 rd day 7 th day 10 th day Control group 147±6,0 cm 2 (100%) 133±5,0 (90,4%) 75±3,0 (51%) 59±5,5 (40,1%) Main group I 141±8,0 cm 2 (100%) 119±5,0 (84,3%) 60±4,0 (42,5%) 43±2,5 (30,5%) Main group II 143±5,0 cm 2 (100%) 111±5,0 (77,6%) 48±4,0 (33,5%) 39±2,0 (27,3%) Studying the planimetric parameters obtained, we can conclude that the average daily rate of decrease in the area of purulent wounds in the control group was - 5.99% in 10 days, in the main group I, with the combined use of photodynamic therapy with photosensitizer methylene blue, the rate of shortening of the wound surface was -6.9 %, and in the main group II, with the combined use of photodynamic therapy and a CO2 laser, the rate of shortening of the wound surface was higher and amounted to –7.2%. In the course of monitoring the patients of the main group during the year, none of the patients showed the formation of keloid or gross hypertrophic scars. The scar tissue did not protrude above the skin level, was smooth, did not deform the skin and subcutaneous tissue, and was not adhered to the underlying tissues. The study of the microbiology of purulent wounds shows that those obtained from patients of three groups were contaminated with microorganisms, i.e. growth was observed in all samples (100%). From 105 examined patients, 124 strains of microbes were isolated, of which 86 (82%) were monocultures, 19 (18%) strains were found in an association of two types of microbes. In 9 (47.4%) cases, two types of staphylococci were sown; in 6 (31.5%) cultures hemolytic streptococci were associated with staphylococci and in 1 (5.3%) - E. coli. In one case, Candida fungi were excreted with E. coli, Proteus, and streptococci. The dominant pathogens of HVD were gram-positive microorganisms - 124/112 (91.4%), among which the leading position was occupied by staphylococci 83%, represented, in most of the crops, by St. aureus (92%). Representatives of the gram- negative flora were: Proteusspp. (3 / 2.5%), Ps. aeruginosae (7/6%), E. coli (2 / 1.5%). A comparative analysis of the data obtained from the three examined groups of patients showed that all the methods of treatment used had an effect to one degree or another on the causative agent of the purulent-inflammatory process. The differences between these groups were manifested in the timing of the elimination of the pathogen (Figure 23). 6 Year 2022 Global Journal of Medical Research Volume XXII Issue I Version I ( D ) F © 2022 Global Journals Optimization of Treatment Methods for Purulent-Destructive Soft Tissue Diseases through the use of Laser Treatment Methods Fig. 23: Frequency and term of pathogen elimination in comparative groups As shown in the diagram, the change in the drillability of microbes from purulent foci occurs by the seventh day. In 32% of patients in the control group who received traditional treatment, there was no growth of 0 0 32 12 59 36 67 0 20 40 60 80 100 120 140 160 180 3rd day 7th day 10th day Frequency and term of pathogen elimination