Global Journal of Science Frontier Research, G: Bio-Tech & Genetics, Volume 22 Issue 2

Manipulation technologies (CRISPR) and especially of artificial creation of genomes will have to respect these laws of nature. In ( Strecker et al., 2019 ) by using DNA sequences referred to as transposons, or “jumping genes” (genes that can change their position within the genome), a team from MIT led by NYSCF – Robertson Stem Cell Investigator Dr . Feng Zhang has created a new version of CRISPR (called CRISPR-associated transposase, or “CAST”) that can insert functional DNA sequences into the genome without making cuts, which can often lead to unintended damage. What about for the FUTURE ? There are theoretical new background for Biology and Genetics, these tracks are MATHEMATICS (Perez § Montagnier L., 2021). A cknowledgements We especially thanks Dr. Robert Friedman M.D. practiced nutritional and preventive medicine in Santa Fe, New Mexico, woldwide expert on Golden ratio Life applications (https://tinyurl.com/y9dxaauv) and Diego Rapoport (mathématician), Retired Full Professor, UNQ & Universidad de Buenos Aires, Instituto Balseiro Bariloche; CONICET (Argentina); Universidade de São Paulo & PUC-Rio (Brasil) ; Univ. Autónoma Metropolitana de México ; Univ. of Tel Aviv ; Univ of Bío Bío (Chile). Patagonia, Argentina. We also thank Marco F. Paya Torres (M.D Alicante), professor E.G. Rajan, Founder President PENTAGRAM Research Centre (P) Limited Hyderabad INDIA, the French biologist Pr. François Gros for its strong comments on HGO and cancer mutations (Pasteur institute, codiscoverer of RNA messenger with James Watson and Walter Gilbert), Professor Andras Pellionisz (HolGenTech), Professor Sergey V. Petoukhov (Dr. Phys.-Math. Sci, Grand Ph.D., Full Professor, Laureate of the State prize of the USSR), Volkmar Weiss (Dr. rer. nat. habil. Dr. phil. Habil. Leipzig, Germany), and RIP Pr. Luc Montagnier, medicine Nobel prizewinner for their interest in my research of biomathematical laws of genomes. R eferences R éférences R eferencias 1. Blount B. A. et al, Construction of anEscherichia coli genome with fewer codons sets records, Nature 569, 492-494 (2019) doi: 10.1038/d41586-019-01584-x, 2. ht tps://www.nature.com/articles/d41586-019-01584- x 3. Breuer M. et al., Essential metabolism for a minimal cell., Elife. 2019 Jan 18; 8 Published online 2019 Jan 18. doi: 10.7554/eLife.36842, https://www.ncbi . nlm.nih.gov/pubmed/30657448/ 4. Callaway Ewen,‘Minimal’ cell raises stakes in race to harness synthetic life, Nature 531, 557–558 (31 March 2016) doi: 10.1038/531557a, https://www. nature.com/news/minimal-cell-raises-stakes-in-race- to-harness-synthetic-life-1.19633 5. Fedoroff, N.V. 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